Kv Channel Interacting Protein 1 (KCNIP1) (N-Term), (Isoform 1)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human, mouse, rat
Isotype
n/a
Format
serum
Size
100 μL
Concentration
n/a
Applications
Immunohistochemistry (IHC),Western Blotting (WB)
Reviews / Ratings
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Description
Function: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Probably modulates channels density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Seems to be involved in KCND2 trafficking to the cell surface.Subcellular location: Cell membrane, Peripheral membrane proteinTissue specificity: Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus. Also known as: Kv channel-interacting protein 1, A-type potassium channel modulatory protein 1, Potassium channel-interacting protein 1, Vesicle APC-binding protein, KCHIP1, VABP.
Immunogen
A synthetic peptide from n-terminal region of rat KCNIP1, isoform 1 conjugated to an immunogenic carrier protein was used as the antigen.