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Description
Rabbit polyclonal antibody to detect BRD3 in human mouse and rat samples. The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as ``readers'' of histone acetylation marks regulating the transcription of target promoters. The BET family of proteins, defined by tandem Bromodomains and an Ext
Immunogen
Synthetic peptide at N-terminal
Other Names
Bromodomain containing 3, isoform CRA_b, ORFX; RING3L; Bromodomain containing protein 3; RING3-like protein