Recombinant Human Mitotic spindle assembly checkpoint protein MAD2A (MAD2L1)
Description
Purity > 90% as determined by SDS-PAGE. MW: 39.4kDa. Full Length of Mature Protein: 2-205aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Component of the spindle-assbly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Mitotic arrest deficient 2-like protein 1; MAD2-like protein 1