A natural diterpene that increases glutathione S-transferase expression and activity in vivo; inhibits LPS-induced NO and PGE2 production (IC50 = 54 and 23 μM, respectively) in RAW macrophages; blocks the proliferation of endothelial cells (IC50 = 50 μM) and inhibits endothelial migration, invasion, and tube formation
Size
5 mg
Concentration
n/a
Applications
n/a
Other Names
natural products inflammation angiogenesis glutathione S-transferase cancers diterpene anti-inflammatory antiinflammatory anti-angiogenic antiangiogenic mucosa mice cafestol rat livers RAW macrophages LPS NO prostaglandin E2 PGE2 PGs nitric oxide