Non-viable cell pellet was generated from cell line WM3623. WM3623 is a metastatic human melanoma cell line. This cell line was established from a right lymph node metastasis site in a 48-year-old male with level V metastatic malignant melanoma. This cell line contains a Q61K mutation at position 61 in the N-RAS gene which causes increased signaling via the extracellular signal-regulated MAPK/ERK kinase pathways to enhance proliferation. WM3623 cells produce xenograft tumors when injected into immunocompromised mice.
Size
1 each
Concentration
n/a
Applications
Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation.
Other Names
Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft