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Description
Mouse Anti-BUB1 (AA 221-270) Recombinant Antibody (CBYY-0937). This product is mouse antibody that recognizes BUB1. The antibody CBYY-0937 can be used for immunoassay techniques such as: ELISA, IF, IP, WB. This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forMouse of cancer. Alternate splicing results in multiple transcript variants.
Immunogen
Recombinant protein corresponding to aa281-419 from human BUB1