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Description
RABBIT ANTI HUMAN CD243. This item detects CD243, also known as MDR1 (multi-drug resistance protein 1) and P-glycoprotein. CD243 is a 170kDa membrane-associated protein which functions as an ATP-dependent drug efflux pump with broad substrate specificity. CD243 is highly expressed in the kidney, liver, adrenal gland and intestine, suggesting a primary role in the secretion of metabolites into bile, urine and the lumen of the intestinal tract. CD243 also prevents the accumulation of tox
Immunogen
Synthetic peptide: cytoplasmic domain of human CD243, conjugated to keyhole limpet hemocyanin.Histology Positive Control Tissue: Adrenal, cortex.
Other Names
multidrug resistance protein 1; Multidrug resistance protein 1; multidrug resistance protein 1; P-glycoprotein 1; colchicin sensitivity; doxorubicin resistance; ATP-binding cassette, sub-family B (MDR/TAP), member 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD_antigen: CD243, ABCB1; ABCB1; CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170; MDR1; PGY1