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| Antigenic Specificity | CASPASE-2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | n/a |
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| Size | 0.05 mg |
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| Concentration | IgG concentration 1.0mg/ml |
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| Applications | Immunohistology Paraffin*, Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RABBIT ANTI HUMAN CASPASE-2. This item recognises human caspase-2, a 53 kDa member of the cysteine-aspartic acid protease (caspase) family. Caspase-2 is required for the permeabilisation of the mitochondria and the resulting amplification of caspase activity, in response to cytotoxic stress. Cytotoxic stress induced proteolytic cleavage of the caspase-2 proenzyme forms an active caspase which cleaves other caspases in a cascade. This leads to the release of cytochrome c and Smac from m |
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| Immunogen | Synthetic peptide corresponding to 6 amino acid sequence from the amino-terminus of human Caspase-2.Histology Positive Control Tissue: Human placenta |
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| Other Names | caspase-2 isoform 2; Caspase-2; caspase-2; neural precursor cell expressed developmentally down-regulated protein 2; protease ICH-1; protein phosphatase 1, regulatory subunit 57; caspase 2, apoptosis-related cysteine peptidase; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1Cleaved into the following 3 chains:Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12, CASP2; CASP2; ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57; ICH1; NEDD2; CASP-2 |
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| Gene, Accession # | Gene ID: 835, NCBI: NP_001215.1, UniProt: P42575 |
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| Catalog # | MBS222887 |
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| Price | |
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| Order / More Info | CASPASE-2 Antibody from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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