Fructose bisphosphate aldolase A, also known as Aldolase A is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. It is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Deficiency has been associated with myopathy and hemolytic anemia. Recombinant human Aldolase A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW: 41.5 kDa (384 aa, 1-364 aa + His Tag), confirmed by MALDI-TOF. Purity ≥95%
Size
100 μg
Concentration
1 mg/ml
Applications
RUO
Other Names
Fructose bisphosphate Aldolase A, ALDOA, ALDA, GSD12