Background/Introduction: Alpha 1-Antitrypsin is a 52 kDA serine protease inhibitor (serpin) in blood, which protects tissue from enzym~s from inflammatory cells, especially elastase. In certain acute phase inflammatory reactions, A1AT is elevated I~ order to limit the damage caused by activated neutrophil granulocytes and their enzyme elasta~e. ~isorders of A 1AT include A 1AT deficiency, a hereditary disorder that can lead to severe tissue breakdown during inflammation. This may result in pulmo