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Description
Mouse Anti-BAG2 Recombinant Antibody (CBYY-1814). This product is mouse antibody that recognizes BAG2. The antibody CBYY-1814 can be used for immunoassay techniques such as: ELISA, WB. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Immunogen
Partial recombinant corresponding to aa102-212 from BAG2 (NP_004273) with GST tag. MW of the GST tag alone is 26kD