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Description
Mouse Anti-IL10RA Recombinant Antibody (714212). This product is Mouse antibody that recognizes IL10RA. The antibody 714212 can be used for immunoassay techniques such as: WB, FC, CyTOF. The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not prote