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Description
TrkB(Y817) (2A1) Monoclonal Antibody. ? Target Background: Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodi
Immunogen
Synthetic peptide derived from human TrkB(Y817), around 800-850aa (phospho Y817).