2-428. Full length. MW: 52.2kD. Purity >90% as determined by SDS-PAGE. Plays a role in modulating the ganglioside content of the lipid bilayer at the level of membrane-bound sialyl glycoconjugates.
Cloning, expression, and chromosomal mapping of a human ganglioside sialidase.Wada T., Yoshikawa Y., Tokuyama S., Kuwabara M., Akita H., Miyagi T.Biochem. Biophys. Res. Commun. 261:21-27(1999) Identification and expression of NEU3, a novel human sialidase associated to the plasma membrane.Monti E., Bassi M.T., Papini N., Riboni M., Manzoni M., Venerando B., Croci G., Preti A., Ballabio A., Tettamanti G., Borsani G.Biochem. J. 349:343-351(2000) Complete sequencing and characterization of 21,243 f