Immunocytochemistry: 1-2 μg/mL, Immunofluorescence: 1-2 μg/mL, Western Blot: 2-3 μg/mL
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Description
mTOR Antibody (7H13L18), ABfinity? Rabbit Monoclonal. Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation.