Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunoprecipitation: 2 μg, Western Blot: 1:100-1:1000
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Description
mTOR Polyclonal Antibody. Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation.