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Description
Rabbit Anti-NPHS1 Recombinant Antibody (Y17-R). This product is a Rabbit antibody that recognizes NPHS1. The antibody Y17-R can be used for immunoassay techniques such as: ELISA, IHC, WB. This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the