1-259aa, Full length protein. MW: 28,339 Da. Purity >85% (SDS-PAGE). In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. This protein is similar to Ke6 and is a member of the short-chain dehydrogenase su