2-651aa, Full Length of Mature Protein. MW: 71,618 Da. Purity >85% (SDS-PAGE). This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu proteinRNA helicase IIDEAD box polypeptide 21, and interacts with androgen receptor (AR). It functi
[E3 SUMO-protein ligase PIAS1; E3 SUMO-protein ligase PIAS1; E3 SUMO-protein ligase PIAS1; protein inhibitor of activated STAT 1; DEAD/H box-binding protein 1; Protein inhibitor of activated STAT protein 1; RING-type E3 ubiquitin transferase PIAS1Curated]