產(chǎn)品名稱 Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 from MYBIOSOURCE INC.
    產(chǎn)品貨號(hào) MBS964250
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià),電話:010-67529703
    產(chǎn)品規(guī)格 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (E-Coli)
    產(chǎn)品品牌 MYBIOSOURCE INC.
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameRecombinant Mouse E3 ubiquitin-protein ligase Mdm2
    Description1-489aa; Full Length. MW: 58.6kD. Purity >90% as determined by SDS-PAGE. E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 pr
    Size0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (E-Coli)
    Concentrationn/a
    Applicationsn/a
    Other Names[Double minute 2 protein; Oncoprotein Mdm2; p53-binding protein Mdm2]
    Gene, Accession, CAS #Mdm2, Gene ID: 17246, Accession: NP_001275515.1
    Catalog #MBS964250
    Price
    Order / More InfoRecombinant Mouse E3 ubiquitin-protein ligase Mdm2 from MYBIOSOURCE INC.
    Product Specific ReferencesTumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line.Fakharzadeh S.S., Trusko S.P., George D.L.EMBO J. 10:1565-1569(1991) Genomic organization of the mouse double minute 2 gene.Jones S.N., Ansari-Lari M.A., Hancock A.R., Jones W.J., Gibbs R.A., Donehower L.A., Bradley A.Gene 175:209-213(1996) The organization and expression of the mdm2 gene.de Oca Luna R.M., Tabor A.D., Eberspaecher H., Hulboy D.L., Worth L.L., Colman M.S., Finlay C.A.,
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