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Description
CANX/Calnexin Polyclonal Antibody, HRP Conjugated. ? Target Background: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte
Immunogen
KLH conjugated synthetic peptide derived from human CANX. Immunogen Range: 542-592/592
Other Names
CNX; P90; IP90; Calnexin; Major histocompatibility complex class I antigen-binding protein p88; CANX