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Description
Mouse Anti-TNFRSF18 Recombinant Antibody (CBFYC-3173). This product is mouse antibody that recognizes TNFRSF18. The antibody CBFYC-3173 can be used for immunoassay techniques such as: ELISA(Det), ELISA FC, Neut, WB. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Immunogen
Recombinant human GITR/TNFRSF18 Gln26-Glu161 (Thr43Ala)
Other Names
TNF Receptor Superfamily Member 18; Glucocorticoid-Induced TNFR-Related Protein; Activation-Inducible TNFR Family Receptor; AITR; GITR; Tumor Necrosis Factor Receptor Superfamily, Member 18