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Description
Rat Anti-TNFRSF18 Recombinant Antibody (AP-MAB0860). This product is antibody recognizes TNFRSF18. The antibody AP-MAB0860 immunoassay techniques such as: FC. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]