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Description
Mouse Anti-CFB Recombinant Antibody (42286). This product is antibody recognizes CFB. The antibody 42286 immunoassay techniques such as: IHC-F, ELISA, IHC-F, WB. This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility
Immunogen
This item recognises the Bb fragment of 90 kDa human complement factor B, present in blood serum.