bovine, equine, guinea pig, human, mouse, porcine, rabbit, rat
Isotype
n/a
Format
purified
Size
100 μl
Concentration
n/a
Applications
Western Blot: 1.0 μg/mL
Reviews / Ratings
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Description
PAOX Polyclonal Antibody. Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.