An inhibitor of c-Src and Abl kinases (IC50s = 1.2 and 1 nM, respectively); inhibits the kinases EPHB2, TrkA, TrkB, and TXK (IC50s = 8.5, 22, 27, and 40 nM, respectively) among others; inhibits Src-dependent cell proliferation (IC50 = 100 nM); reduces tumor growth in unstaged and staged Src-transformed fibroblast mouse xenograft models at 30 or 25 mg/kg, respectively, twice per day; induces complete tumor regression in a K562 mouse xenograft model at 100 mg/kg once per day for five days