Purity: > 95% by SDS - PAGE Format: Liquid. In 10mM Sodium citrate buffer (pH 3.5), 10% glycerol. Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic protein family which belongs to the TGF-beta superfamily. This protein is a vital regulatory molecule that functions throughout bone and cartilage development, specifically tooth development, limb formation, bone induction, and fracture repair. In human embryonic development, BMP- 4 is required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. And it is overexpressed in patients with fibrodysplasia ossificans progressiva. Recombinant BMP-4 was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Size
0.5mg , 100ug, 20ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Bone morphogenetic protein 4, BMP-2B, DVR4, Bone morphogenetic protein 4 BMP 4, BMP2B, BMP2B1, ZYME, BMP4