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Description
Rabbit Anti-PAK2 Recombinant Antibody (CBYC-P145). Provided herein is a Rabbit monoclonal antibody against Human P21 (RAC1) Activated Kinase 2. The antibody can be used for immunoassay techniques, such as WB, IHC-P, ICC, FC. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.