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Description
Phospho-Caspase 9 (Thr125) Antibody detects endogenous levels of Caspase 9 only when phosphorylated at Threonine 125. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.