An amylin analog; stimulates cAMP production in HEK293 cells expressing human AMY1a, AMY2a, and AMY3a (EC50s = 0.35, 22.9, and 0.89 nM, respectively); inhibits human islet amyloid polypeptide fibrilization in a concentration-dependent manner; reduces brain levels of Aβ40 and increases spontaneous alternation in the Y-maze in the Tg2576 transgenic mouse model of Alzheimer's disease at 200 pg/kg,