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Description
Mouse Anti-WWTR1 Recombinant Antibody (CBYJT-5582). Provided herein is a Mouse monoclonal antibody, which binds to WWTR1 (WW Domain Containing Transcription Regulator 1). The antibody can be used for immunoassay techniques, such as WB, IHC, IHC-P. WWTR1 is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates Y
Immunogen
Full length human recombinant protein of human WWTR1(NP_057287) produced in HEK293T cell
Other Names
WW Domain Containing Transcription Regulator 1; TAZ; WW Domain-Containing Transcription Regulator Protein 1; Transcriptional Co-Activator With PDZ-Binding Motif; Transcriptional Coactivator With PDZ-Binding Motif