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Description
Mouse Anti-XRCC5 Recombinant Antibody (F3). Provided herein is a Mouse monoclonal antibody against Human XRCC5. The antibody, clone F3, can be used for immunoassay techniques, such as IF, WB. XRCC5 is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. XRCC5 binds to DNA may be mediated by XRCC6. XRCC5 is involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. A rare microsatellite polymorphism in XRCC5 is associated with cancer in patients of varying radiosensitivity.