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Description
EVI1 Polyclonal Antibody. The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Immunogen
n/a
Other Names
MECOM; MDS1 and EVI1 complex locus; AML1-EVI-1; EVI1; MDS1; MDS1-EVI1; MGC163392; MGC97004; PRDM3; AML1-EVI-1 fusion protein; ecotropic viral integration site 1; myelodysplasia syndrome 1; myelodysplasia syndrome-associated protein 1; oncogene EVI1; zinc finger protein Evi1