Purified (SDS-PAGE). This nuclear receptor functions as a transcription factor and plays an important role in controlling differentiation and fatty acid metabolism. Activation of this receptor appears to be vital in modulating the expression of metabolic control proteins and consequently controlling fatty acid metabolism in cardiac muscle. This marker may be a useful drug target for therapeutic intervention in cardiac disease. PPAR gamma is also involved in the pathogenesis of important metabolic disorders such as obesity and non-insulin-dependent diabetes (NIDDM). Source: Recombinant corresponding to human PPARG, fused to 6x His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~59.2kD Applications: Suitable for use in Western Blot as a control.
Size
10ug
Concentration
n/a
Applications
WB
Other Names
PPARG, Recombinant, Human (Peroxisome Proliferator-activated Receptor gamma, PPAR-gamma, Nuclear Receptor Subfamily 1 Group C Member 3, NR1C3)