產(chǎn)品名稱 Alpha-Ketoglutarate Dehydrogenase Activity Colorimetric Assay Kit from BIOVISION, INC.
    產(chǎn)品貨號(hào) K678-100
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
    產(chǎn)品規(guī)格 100 assays
    產(chǎn)品品牌 BIOVISION, INC.
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameAlpha-Ketoglutarate Dehydrogenase Activity Colorimetric Assay Kit
    Descriptionα-Ketoglutarate Dehydrogenase (α-KGDH) (EC 1.2.4.2) is a key enzyme in the citric acid cycle. It forms an enzyme complex with dihydrolipoamide succinyl transferase (E2) and dihydrolipoamide dehydrogenase (E3). α-KGDH converts α-ketoglutarate into succinyl-CoA in the presence of NAD and CoA. It is highly regulated by intracellular ATP/ADP and NADH/NAD ratios and calcium. In humans, decreased KGDH activity can lead to neurodegenerative diseases such as Alzheimer's disease. Recent studies show that α-KGDH is a target of oxidative stress; reactive oxygen species (ROS) inhibit KGDH activity which diminishes its critical function and can cause a bioenergetic deficit. BioVision's α-KGDH assay kit provides a quic
    Size100 assays
    Concentrationn/a
    Applications? Measurement of α-Ketoglutarate dehydrogenase activity in various tissues/cells? Analysis of cell signaling pathways such as citrate acid cycle, lysine degradation or tryptophan metabolism in various cell types
    Other Namesn/a
    Gene, Accession, CAS #n/a
    Catalog #K678-100
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    Order / More InfoAlpha-Ketoglutarate Dehydrogenase Activity Colorimetric Assay Kit from BIOVISION, INC.
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