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| Antigenic Specificity | DR4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | Alexa Fluor? 750 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DR4 Polyclonal Antibody, Alexa Fluor? 750 Conjugated. ? Target Background: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. |
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| Immunogen | KLH conjugated synthetic peptide derived from human DR4 . Immunogen Range: 420-468/468 |
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| Other Names | DR4; APO2; CD261; TRAILR1; TRAILR-1; Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; TNFRSF10A |
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| Gene, Accession # | Gene ID: 8797, SwissProt: O00220 |
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| Catalog # | bs-0591R-A750 |
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| Price | |
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| Order / More Info | DR4 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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