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Description
Mouse Anti-EIF4EBP1 (AA 1-118) Recombinant Antibody (4F3-H2). This product is mouse antibody that recognizes EIF4EBP1. The antibody 4F3-H2 can be used for immunoassay techniques such as: ELISA, IF, PLA, WB. This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation o
Immunogen
EIF4EBP1 full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen sequence: MSGGSSCSQT PSRAIPATRR VVLGDGVQLP PGDYSTTPGG TLFSTTPGGT RIIYDRKFLM ECRNSPVTKT PPRDLPTIPG VTSPSSDEPP MEASQSHLRN SPEDKRAGGE ESQFEMDI
Other Names
Eukaryotic Translation Initiation Factor 4E Binding Protein 1; Phosphorylated Heat- And Acid-Stable Protein Regulated By Insulin 1; EIF4E-Binding Protein 1; 4E-BP1; PHAS-I; Eukaryotic Translation Initiation Factor 4E-Binding Protein 1; 4EBP1; BP-1