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Description
Rat Anti-EIF2S1 (AA 1-315) Recombinant Antibody (CBFYE-0659). This product is rat antibody that recognizes EIF2S1. The antibody CBFYE-0659 can be used for immunoassay techniques such as: WB. The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987).
Immunogen
E.coli-derived recombinant human eIF2 alpha, Met1-Asp315