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Description
Mouse Anti-DCK Recombinant Antibody (2F10). Provided herein is a Mouse monoclonal antibody, which binds to Deoxycytidine Kinase (DCK). The antibody can be used for immunoassay techniques, such as ELISA, ICC, IF, WB. DCK is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Immunogen
DCK (NP_000779, 161 a.a. ~ 260 a.a) partial recombinant protein with GST tag.