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Description
KLHL21 Polyclonal Antibody, Alexa Fluor? 555 Conjugated. ? Target Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
Immunogen
KLH conjugated synthetic peptide derived from human KLHL21
Other Names
Kelch like protein 21; KIAA0469; KLHL21; MGC99635; KLH21_HUMAN.