Chromosome 14 Open Reading Frame 1 (C14orf1) (N-Term)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
mouse, human
Isotype
n/a
Format
antigen affinity purified
Size
0.1 mg
Concentration
n/a
Applications
Immunohistochemistry (IHC)
Reviews / Ratings
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Description
ERG28(Probable ergosterol biosynthetic protein 28) has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum. ERG28 may also be responsible for facilitating their interaction. The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). ERG28 acts as a scaffold to tether ERG27 and other 4,4-demethylation-related enzymes, forming a demethylation enzyme complex, in the endoplasmic reticulum. ERG28 interacts with ERG25, ERG26 and ERG27. It also interacts with ERG1, ERG3, ERG5, ERG6 and ERG11.
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse ERG28(Probable ergosterol biosynthetic protein 28)
Other Names
ERG28|NET51|homolog of yeast ergosterol28|T27I1.5|T27I1_5|C7H14orf1