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Description
The triggering receptor expressed on myeloid cells-2 (TREM2) is a membrane protein that interacts with the TYROBP protein. The TREM2 and TYROBP proteins form a complex that transmits chemical signals to activate the cell. This complex is involved in the growth and development of several types of immune cells, particularly dendritic cells and activates these cells, triggering an inflammatory response to injury or disease. And the TYROBP-TREM2 complex also activates cells in the skeletal system and in the brain and spinal cord (central nervous system).
Immunogen
Recombinant human TREM2 (19-161aa) purified from E. coli
Other Names
triggering receptor expressed on myeloid cells 2 isoform 1, triggering receptor expressed on myeloid cells 2, triggering receptor expressed on myeloid cells 2a, TREM-2, Trem2a, Trem2b, Trem2c