Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human
Isotype
n/a
Format
affinity purified
Size
50 μg
Concentration
n/a
Applications
Western Blotting (WB)
Reviews / Ratings
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Description
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
Immunogen
ADH5 antibody was raised using a synthetic peptide corresponding to a region with amino acids KSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIRTVV
Other Names
ADHX|ADHX_DROME|CG6598|Dmel\\CG6598|GSNOR|ODH|Odh|fdh|gfd|gfd/odh|odh|ADH3|wu:fb60b11|ADH-3|FALDH|FDH|GSH-FDH|Adh-5|Adh3|ADH1C|ADH2|ALCOHOL DEHYDROGENASE 2|ATGSNOR1|GLUTATHIONE-DEPENDENT FORMALDEHYDE DEHYDROGENASE|MRH10.4|MRH10_4|PAR2|PARAQUAT RESISTANT 2|S-NITROSOGLUTATHIONE REDUCTASE|sensitive to hot temperatures 5