ARP1 Actin-Related Protein 1 Homolog A, Centractin alpha (Yeast) (ACTR1A)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human, mouse, rat, dog
Isotype
n/a
Format
affinity purified
Size
50 μg
Concentration
n/a
Applications
Western Blotting (WB)
Reviews / Ratings
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Description
ACTR1A is a 42.6 kDa subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
Immunogen
ACTR1 A antibody was raised using a synthetic peptide corresponding to a region with amino acids AIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRP