Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000
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Description
ARPC5 Monoclonal Antibody (OTI2G1). The Arp2/3 (Actin-related protein 2/3) complex consists of seven subunits, all of which are actin-related proteins. The complex is involved in the control of actin polymerization and in mediating the formation of branched actin networks. p16-ARC, also known as ARPC5 (Actin-related protein 2/3 complex subunit 5) or ARC16 (Arp2/3 complex 16 kDa subunit), is a 151 amino acid subunit of the Arp2/3 complex. Thought to play a role in maintaining the integrity of Arp2/3, p16-ARC is a substrate for MAPKAPK-2 which, through phosphorylation of p16-ARC, may participate in Arp2/3 regulatory functions and remodeling of the Actin cytoskeleton. Two isoforms of p16-ARC exist due to alternative splicing events.
Immunogen
n/a
Other Names
ARC16, dJ127C7.3, p16-Arc, Arp2/3 protein complex subunit p16, actin-related protein 2/3 complex subunit 5, arp2/3 complex 16 kDa subunit