Cayman's PPARγ-LBD Ligand Screening Assay Kit provides a convenient fluorescence polarization (FP)-based single-step assay for screening ligands of the PPARγ-Ligand Binding Domain (PPARγ-LBD). In this assay, a ligand of PPARγ is conjugated to fluorescein and is used as the displacement probe. Ligands, agonist, and antagonists of PPARγ-LBD will displace the fluorescent probe leading to a decrease in FP.