Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Western Blot: 1:500-1:2000
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Description
PPM1G Monoclonal Antibody (OTI1C12). The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
Immunogen
n/a
Other Names
Protein phosphatase 2C gamma isoform, PP2C-gamma, Protein phosphatase magnesium-dependent 1 gamma, Protein phosphatase 1C, PPM1C