Immunocytochemistry: 20 μg/mL, Immunofluorescence: 20 μg/mL, Western Blot: 1 μg/mL
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Description
CLEC2A Polyclonal Antibody. CLEC2A (C-type lectin domain family 2 member A), also known as PILAR (proliferation-induced lymphocyte-associated receptor) is involved in modulating T-cell expansion. It is a 32 kDa single-pass type II membrane protein that contains one C-type lectin domain in its extracellular region and belongs to the CTL/CTLD superfamily. CLEC2A is mainly expressed in skin and highly expressed in CD8(+), B lymphocytes and naive CD4(+) T cells. Manipulation of CLEC2A signaling may be important for treatment of autoimmune diseases and cancer.
Immunogen
n/a
Other Names
CLEC2A, C-type lectin domain family 2 member A, Keratinocyte-associated C-type lectin, KACL, Proliferation-induced lymphocyte-associated receptor, PILAR, UNQ579