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Description
PRP8 Polyclonal Antibody. Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
Immunogen
n/a
Other Names
HPRP8, PRP8, PRPC8, RP13, 220 kDa U5 snRNP-specific protein, PRP8 homolog, U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p, apoptosis-regulated protein 1, apoptosis-regulated protein 2, p220, pre-mRNA-processing-splicing factor 8, precursor mRNA processing protein, spl