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Description
Rabbit IgG polyclonal Picoband? antibody for Transthyretin(TTR) detection. Tested with WB, IHC-P in Mouse;Rat. No cross reactivity with other proteins. Transthyretin (TTR) is also known as prealbumin. It is mapped to chromosome region 18q11.2-q12.1. This gene encodes a carrier protein responsible for the transport of thyroid hormones and retinol. The protein consists of a tetramer of identical subunits. Due to increased stability of the tetramer form of this encoded protein in mouse, compared to the human protein, this gene product has a reduced tendency to form amyloid fibrils. In humans, this protein binds beta-amyloid preventing its aggregation and providing a neuroprotective role in Alzheimer's disease.
Immunogen
E.coli-derived mouse Prealbumin recombinant protein (Position: G21-N147). Mouse Prealbumin shares 81% and 94.5% amino acid (aa) sequence identity with human and rat Prealbumin, respectively.